Prim-O-glucosylcimifugin

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Catalog No.	BCN4952
CAS RN	80681-45-4
Molecular Weight	468.45
Molecular Formula	C22H28O11
Database	[PubChem]:382165061 [ChEBI]: [PCIDB]:31084

Definition

Standard InChI

InChI=1S/C22H28O11/c1-22(2,28)15-5-10-12(32-15)6-13-16(20(10)29-3)11(24)4-9(31-13)8-30-21-19(27)18(26)17(25)14(7-23)33-21/h4,6,14-15,17-19,21,23,25-28H,5,7-8H2,1-3H3/t14-,15+,17-,18+,19-,21-/m1/s1

Biological Activity

Prim-O-glucosylcimifugin is main medicinal component of the traditional Chinese drug Saposhnikovia divaricata, can increase concentrations of astragaloside IV and atractylenolide I in the serum, when they were given together.[1]
Prim-O-glucosylcimifugin has inhibition on NO production and DPPH free radical.[2]
Prim-O-glucosylcimifugin and 4′-O-β-D-glucosyl-5-O-methylvisammin-ol con can inhibit the proliferation of smooth muscle cell stimulated by TNF-α and increase the proportion of G0/G1 phase.[3]

Product information

English website: Prim-O-glucosylcimifugin
Japanese website: Prim-O-glucosylcimifugin
Chinese website: Prim-O-glucosylcimifugin

References

[1] Song J, Zheng S R, Jin Y, et al. Planta Med, 2014, 80(3):187-92.
[2] Bo Z, Xin B Y, Xiu W Y, et al. J Asian Nat Prod Res, 2012, 14(9):886-96.
[3] Wang L, Liang R X, et al. China J Chinese Materia Medica, 2008, 33(17):2157-60.
[4] Pin R, Fang B, Li P, et al. Guiding J Trad Chinese Med Pharm, 2010, 16(11):84-6.