Lyoniside

Catalog No. BCN5277
CAS RN 34425-25-7
Molecular Weight 552.6
Molecular Formula C27H36O12
Database [PubChem]:382160163
[ChEBI]:
[PCIDB]:

Definition

Standard InChI

InChI=1S/C27H36O12/c1-34-17-7-13(8-18(35-2)23(17)31)20-15(10-38-27-25(33)22(30)16(29)11-39-27)14(9-28)5-12-6-19(36-3)24(32)26(37-4)21(12)20/h6-8,14-16,20,22,25,27-33H,5,9-11H2,1-4H3/t14-,15-,16+,20+,22-,25+,27+/m0/s1

Biological Activity

Lyoniside and saracoside are cytotoxic to promastigotes and intracellular amastigotes,  
they effectively kill L. donovani amastigotes inside macrophages in vitro , demonstrate strong anti-leishmanial efficacies in BALB/c mice model of leishmaniasis, suggests that these two compounds potential anti-leishmanial candidates. [1]
The synergistic action of lyoniside and triterpene acids was demonstrated in inhibitory effect exerted on germination and growth of Pinus sylvestris .[2]

Product information

English website: Lyoniside
Japanese website: Lyoniside
Chinese website: Lyoniside

References

[1] Saha S, Mukherjee T, Chowdhury S, et al. Biochem Pharmacol, 2013, 86(12):1673-87.
[2] Szakiel A, Voutquenne-Nazabadioko L, Henry M. Phytochem Lett, 2011, 4(2):138-43.
[3] Lee B, Jin B W, Yun B R, et al. Pharm Mag, 2014, 10(10):195-9.