Diacylglycerol Kinase
Diacylglycerol kinases (DGKs) are a group of ten enzymes that metabolize 1,2,diacylglycerol (DAG) to produce phosphatidic acid (PA). They all contain a conserved C′-terminal catalytic domain and two cysteine-rich Zn2+-finger motifs with varied regulatory domains.
Products for Diacylglycerol Kinase
- Cat.No. Product Name Information/Activity
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BCC6662
Dioctanoylglycol
627-86-1
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BCC7279
R 59-022
R 59-022 (DKGI-I) is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 is a 5-HTR antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils.
