PERK
PKR-like ER kinase (PERK, EIF2AK3) is an elF2α kinase that inhibits protein translation. PERK is a type one endoplasmic reticulum (ER) membrane protein which is involved in both the integrated stress response (ISR) and unfolded protein response (UPR).
Products for PERK
- Cat.No. Product Name Information/Activity
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BCC1606
GSK2606414
GSK2606414 is a cell-permeable and orally available protein kinase R-like endoplasmic reticulum (ER) kinase (PERK) inhibitor with an IC50 of 0.4 nM.
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BCC5340
ISRIB (trans-isomer)
ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM.
