HCN Channel
HCN (hyperpolarization-activated, cyclic nucleotide-gated) channels are members of the cyclic nucleotide-regulated channel family along with cyclic nucleotide-gated (CNG) channels. They are cationic channels that open under hyperpolarization.
Products for HCN Channel
- Cat.No. Product Name Information/Activity
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BCC2399
Cesium chloride
Potassium channel blocker; neuroprotective
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BCC6639
YS-035 hydrochloride
89805-39-0
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BCC7286
Zatebradine hydrochloride
Zatebradine (UL-FS-49 (free base)) is a potent inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels with an IC50 values 1.96 µM. Zatebradine blocks the slow inward current through human HCN1, HCN2, HCN3 and HCN4 channels, with IC50 values of 1.83 µM, 2.21 µM, 1.90 µM and 1.88 µM, respectively.
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BCC6884
ZD 7288
ZD7288 is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.
