Heme Oxygenase
Heme oxygenase (HO) catalyzes the degradation of heme. It is a membrane-bound enzyme that cleaves the heme ring at the α -methene bridge to produce bilverdin (which is metabolized further by bilirubin reductase to form bilirubin), iron and carbon monoxide.
Products for Heme Oxygenase
- Cat.No. Product Name Information/Activity
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BCC6776
Tin protoporphyrin IX dichloride
Tin-protoporphyrin IX (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin-protoporphyrin IX (SnPPIX) sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model.
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BCC6775
Zinc protoporphyrin IX
Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2. Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration. Zinc Protoporphyrin has anti-cancer activity.
