Neurotransmission

Neurotransmission, or synaptic transmission, involves the passage of signals by electrical or chemical means from one neuron to another. It allows communication between nerve cells for the propagation of electrical impulses to and from the central nervous system leading to the co-ordination of secretion, muscle contraction and organ function.

Neurotransmission Products Targets

Products for Neurotransmission - Page 70

Cat.No. Product Name Information/Activity
BCC7378 Proxyfan oxalate 177708-09-7
BCC7963 A 331440 dihydrochloride Selective H<sub>3</sub> antagonist
BCC1863 Pitolisant hydrochloride Pitolisant hydrochloride is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM).
BCC7291 Carcinine ditrifluoroacetate 56897-53-1
BCC6781 Clobenpropit dihydrobromide Clobenpropit dihydrobromide is a potent histamine H3R antagonist/inverse agonist with a pEC50 of 8.07 for histamine H3LR. Clobenpropit dihydrobromide acts as partial agonist at histamine H4 receptors (Ki 13 nM). Clobenpropit dihydrobromide also binds to serotonin 5-HT3 receptors (Ki 7.4 nM) and α2A/α2C adrenoceptors (Ki 17.4/7.8 nM). Clobenpropit dihydrobromide increases apoptosis.
BCC7352 Conessine 546-06-5
BCC7357 GT 2016 152241-24-2
BCC7197 Impentamine dihydrobromide 149629-70-9
BCC6793 Iodophenpropit dihydrobromide Iodophenpropit dihydrobromide is a potent and selective histamine H3 receptor antagonist. The binding of [125I]Iodophenpropit is selective, saturable, readily reversible, and of high affinity (KD 0.32 nM).
BCC7842 JNJ 10181457 dihydrochloride 544707-20-2