GABAB Receptor
GABAB receptors are metabotropic G-protein-coupled receptors responsible for mediating the inhibitory effects of GABA alongside ionotropic GABAA and GABAA-ρ receptors. They exist as heterodimers of GABAB1 and GABAB2 subunits, with both required for function.
Products for GABAB Receptor
- Cat.No. Product Name Information/Activity
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BCC1327
Acamprosate calcium
Acamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction.
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BCC4503
(R)-baclofen
(R)-Baclofen(STX209) is a selective GABAB receptor agonist.
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BCN2187
4-Aminobutanoic acid
γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors).
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BCC6012
RuBi-GABA
1028141-88-9
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BCC6626
SKF 97541
127729-35-5
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BCC6988
CGP 35348
Brain penetrant, selective GABA<sub>B</sub> antagonist
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BCC7605
CGP 36216 hydrochloride
GABA<sub>B</sub> antagonist; displays activity at presynaptic receptors
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BCC6990
CGP 46381
123691-14-5
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BCC6989
CGP 52432
CGP52432 is a GABAB receptor antagonist, with an IC50 of 85 nM.
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BCC6934
CGP 54626 hydrochloride
149184-21-4
