OX2 Receptor
The OX2 receptors, also known as hypocretin receptor 2, are located primarily in the cerebral cortex, paraventricular hypothalamus, nucleus accumbens, subthalamic and paraventricular thalamus where they are thought to regulate sleep-wakefulness.
Products for OX2 Receptor
- Cat.No. Product Name Information/Activity
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BCC5877
[Ala11,D-Leu15]-Orexin B
532932-99-3
![[Ala11,D-Leu15]-Orexin B chemical structure](/media/images/struct/BCC5877.png)
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BCC6226
EMPA
EMPA is a high-affinity, reversible and selective orexin OX2 receptor antagonist. [3H]EMPA binds to human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively.
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BCC6139
JNJ 10397049
708275-58-5
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BCC7670
TCS OX2 29
TCS-OX2-29 is a potent, high affinities and selective orexin-2 receptor (OX2R) antagonist with an IC50 value of 40 nM and a pKI value of 7.5. TCS-OX2-29 displays ~250-fold selectivity for OX2 over OX1.
