Products with Metal-chelators bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1282 | Phytic acid |
| Phytic acid is the principal storage form of phosphorus in many plant tissues, especially bran and seeds. It can act as a cofactor in DNA repair by nonhomologous end-joining. It is a trypsin inhibitor, has chelating, antioxidant, anti-inflammatory, and neuroprotective effects, it forms an iron chelate which greatly accelerates Fe2+-mediated oxygen reduction yet blocks iron-driven hydroxyl radical generation and suppresses lipid peroxidation. High concentrations of phytic acid prevent browning and putrefaction of various fruits and vegetables by inhibiting polyphenol oxidase, it may be a substitute for presently employed preservatives. | |
| BCN1285 | Phytin |
| 1. Phytin and magnesium citrate have hypocalciuric effect , they can reduce urinary calcium excretion in rats fed on high-calcium diets. 2. A six-day treatment with phytin can restore the normal level of the liver monooxygenase system components and MMW peptides, also can reduce the level of lactic acid (LA) and increased that of pyruvic acid (PA) in liver tissues, which lead to a sharp drop in the LA/MA ratio indicative of a decrease in the extent of hypoxia. 3. Individually phytin, EDTA and copper (Cu2+) have inhibitory effect on growth of Gram positive as well as Gram negative bacteria, phytin preferentially protects only Gram negative bacteria from Cu 2+ ion toxicity,phytin also has chelating ability. | |
| BCN2774 | Thonningianin A |
| Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor. Thonningianin A has anti-cancer and antioxidant properties, involves radical scavenging, anti-superoxide formation and metal chelation. | |
| BCN3143 | 1,2-Didehydrotanshinone IIA |
| 1. 1,2-Didehydrotanshinone IIA shows inhibitory effects against acetyl- (AChE) and butyrylcholinesterase (BChE). 2. 1,2-Didehydrotanshinone IIA possesses metal-chelation capacity. | |
| BCN3222 | Miltipolone |
| 1. Miltipolone possibly acts as a Fe(2+) chelator to conduct its inhibitory activity. 2. Miltipolone is a good and broad-spectrum inhibitor against the growth of cancer cells. | |
