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Natural Products from Aconitum karakolicum

Natural Products Isolated from Aconitum karakolicum

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Natural Products from Aconitum karakolicum

1 natural product associated with Aconitum karakolicum

Natural products and bioactive compounds from Aconitum karakolicum
Catalog No. Product Name CAS Number COA
BCN2800 12-Epinapelline
12-Epinapelline chemical structure
110064-71-6 COA

References

8β-Acet-oxy-14α-benzo-yloxy-N-ethyl-3α,10β,13β,15α-tetra-hydr-oxy-1α,6α,16β-trimeth-oxy-4β-(methoxy-methyl-ene)aconitane: aconifine from Aconitum karakolicum Rapaics.[Pubmed: 21582830]


The title compound, C(34)H(47)NO(12), is the norditerpenoid alkaloid aconifine isolated from the leaves and tubers of Aconitum karakolicum Rapaics. It has a lycoctonine carbon skeleton and contains four six-membered rings and two five-membered rings; its geometry is similar to that observed in other lycoctonine-type diterpenoid alkaloids. There are two intra-molecular O-H⋯O hydrogen bonds which close five- and seven-membered pseudo-rings, respectively. In the crystal, two inter-molecular O-H⋯O hydrogen bonds cross-link the mol-ecules into double chains along the a axis.


Norditerpenoid alkaloids from Aconitum karakolicum Rapaics.[Pubmed: 16156092]


Two new norditerpenoid alkaloids, acofamine A (1) and acofamine B (2) were isolated from the aerial parts of Aconitum karakolicum Rapaics. The structures of these compounds were established by spectroscopic methods.