Ainsliaea yunnanensis
Ainsliaea yunnanensis
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Natural products/compounds from Ainsliaea yunnanensis
- Cat.No. Product Name CAS Number COA
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BCN5628
Echinocystic acid510-30-5
Instructions
Guaianolide sesquiterpenoids from Ainsliaea yunnanensis.[Pubmed: 28411482]
None
Triterpenoids from Ainsliaea yunnanensis Franch. and Their Biological Activities.[Pubmed: 27827998]
None
New Sesquiterpenenoids from Ainsliaea yunnanensis.[Pubmed: 27509491]
Investigation of the ethanol extract of the whole plant of Ainsliaea yunnanensis led to the isolation of four new dimeric sesquiterpene lactones, ainsliadimer F-I (1-4), together with seven known dimeric sesquiterpene lactones (5-11) and ten sesquiterpenes (12-21). Their structures were elucidated by spectroscopic methods. The relative stereochemistry of ainsliadimer F was further confirmed by single crystal X-ray diffraction analysis. Compounds 1-21 were tested for the inhibition of nuclear factor kappa B (NF-κB) in the 293-NF-κB-luciferase reporter cell line induced by lipopolysaccharide (LPS), and Compounds 5, 18, 20 and 21 were further tested for the production of TNF-α, IL-1β, IL-6 and IL-10 in RAW 264.7 macrophages induced by LPS. Compounds 5, 18, 20 and 21 exhibited significant activity in anti-inflammatory activity assays.
[Triterpene compounds of Ainsliaea yunnanensis].[Pubmed: 24558876]
The compounds of Ainsliaea yunnanensis were isolated and purified by various kinds of column chromatography methods and their structures were determined by spectroscopic data analysis. Twelve compounds were obtained from the petroleum ether of ethanolic extract of A. yunnanensis and elucidated as bauerenyl acetate (1), bauerenol (2), alpha-amyrin (3), psi-taraxasterol (4), beta-amyrin (5), echinocystic acid (6), multiflorenol (7), 3beta-hydroxy-olean-18-ene germanicol (8), 3beta-hexadecanoyl-12-oleanen-11-one (9), fernenol (10), fern-7-en-3beta-ol (11), and lupeol (12). All compounds were isolated from this genus for the first time except compound 1, 3, 5 and 10, and they were all isolated from this plant for the first time.
[GC-MS analysis of low polar components from Ainsliaea yunnanensis].[Pubmed: 23750411]
To analyze the chemical constituents of low polar components from ethanol extract of Ainsliaea yunnanensis.
