Aster flaccidus
Aster flaccidus
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Natural products/compounds from Aster flaccidus
- Cat.No. Product Name CAS Number COA
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BCN5946
Liquiritigenin578-86-9
Instructions
The phenylpropanoids of Aster flaccidus.[Pubmed: 19686819]
Aster flaccidus bge has been used as traditional medicine in northwestern China. Two new phenylpropanoids (1-2) including one lignan: (7'R, 8S)-9'-lariciresinol-(alpha-methyl)-butanoate (1), 5,9-dimethoxyl-7-(alpha-methyl)-butanoxyl-phenyl-2E-propenol-(alpha-methyl)-butanoate (2) isolated from the chloroform extract of the root of Aster flaccidus bge were identified by means of extensive spectroscopic studies: 1D and 2D NMR spectra as well as HRMS analysis. They have not obvious anti-HIV-1 therapeutic activity (TI=1.0-1.1) compared with AZT (TI=55,556) as the result of the determination of their in vitro anti-HIV-1 activity while compound 2 displays strong antitumor activity against BEL 7402 (human liver carcinoma) with cisplatin as a positive control and the effect increases with the measuring-time going on (24 h, IC(50): 106.67+/-8.47 microM - 72 h, IC(50): 50.51+/-6.11 microM).
Two new terpenoid glucosides from Aster flaccidus.[Pubmed: 17135041]
Two new terpenoid glucosides, namely 2-O-beta-D-glucopyranoside-vicodiol (1) and 10-O-beta-D-glucopyranoside-oplopanone (2), along with seven known compounds, were isolated from the aerial part of Aster flaccidus (composite), a traditional Chinese herb medicine. The structures of 1 and 2 were established by spectroscopic methods, especially 2D NMR experiments.
