Caragana changduensis
Caragana changduensis
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Natural products/compounds from Caragana changduensis
- Cat.No. Product Name CAS Number COA
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BCN5946
Liquiritigenin578-86-9
Instructions
[Chemical Constituents from Caragana changduensis].[Pubmed: 30079714]
To study the chemical constituents of the red heartwood of the stems and roots of Caragana changduensis.
[Isoflavonoids from Caragana changduensis and their nitric oxideinhibitory activities].[Pubmed: 26790296]
Ten isoflavonoids were isolated from the heartwoods of Caragana changduensis Lion f. by means of various column chromatographic techniques. Based on the detailed spectral data analysis (MS and NMR), as well as comparison with the literatures, their chemical structures were determined as 7,2'-dihydroxy-8,4'-dimethoxyisoflavone (1), 4'-hydroxy-7,3'-dimethoxyisoflavone (2), 5, 7, 4'-trihydroxy-2',5'-dimethoxyisoflavone (3), prunetin (4), afrormosin (5), odoratin (6), genistein (7), texasin (8), pratensein (9), and 6,7,3'-trihydroxy-4'-methoxyisoflavone (10). Among them, compounds 1-3 and 9-10 were isolated from the Caragana genus for the first time. All the compounds were obtained from this species for the first time. In the preliminary assays, compounds 1, 2, 6, and 7 possessed significant inhibitory effects on NO production, with IC50 values of 48.12, 25.32, 62.71, 43.59 μmol x L(-1), respectively.
