Natural Products from Caragana changduensis
Natural Products Isolated from Caragana changduensis
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- Natural product compounds selected from diverse chemical and biological sources.
- Broad structural diversity and coverage of biological activities.
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Natural Products from Caragana changduensis
1 natural product associated with Caragana changduensis
| Catalog No. | Product Name | CAS Number | COA |
|---|---|---|---|
| BCN5946 |
Liquiritigenin
|
578-86-9 | COA |
References
[Chemical Constituents from Caragana changduensis].[Pubmed: 30079714]
To study the chemical constituents of the red heartwood of the stems and roots of Caragana changduensis.
[Isoflavonoids from Caragana changduensis and their nitric oxideinhibitory activities].[Pubmed: 26790296]
Ten isoflavonoids were isolated from the heartwoods of Caragana changduensis Lion f. by means of various column chromatographic techniques. Based on the detailed spectral data analysis (MS and NMR), as well as comparison with the literatures, their chemical structures were determined as 7,2'-dihydroxy-8,4'-dimethoxyisoflavone (1), 4'-hydroxy-7,3'-dimethoxyisoflavone (2), 5, 7, 4'-trihydroxy-2',5'-dimethoxyisoflavone (3), prunetin (4), afrormosin (5), odoratin (6), genistein (7), texasin (8), pratensein (9), and 6,7,3'-trihydroxy-4'-methoxyisoflavone (10). Among them, compounds 1-3 and 9-10 were isolated from the Caragana genus for the first time. All the compounds were obtained from this species for the first time. In the preliminary assays, compounds 1, 2, 6, and 7 possessed significant inhibitory effects on NO production, with IC50 values of 48.12, 25.32, 62.71, 43.59 μmol x L(-1), respectively.