Gynostemma longipes
Gynostemma longipes
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Natural products/compounds from Gynostemma longipes
- Cat.No. Product Name CAS Number COA
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BCN1207
Gypenoside XLIX94987-08-3
Instructions
Damarane-type Saponins from Gynostemma longipes and their Cytotoxic Activity.[Pubmed: 26434113]
Two new damarane-type saponins, named gylongiposides II-III (1 and 2), along with one known compound, (23S)-3β,20ξ,21ξ-trihydroxy-19-oxo-21,23-epoxydammar-24-ene 3-O-α-L-rhamnopyranosyl-(1-->2)-[-D-xylopyranosyl-(1-->3)]-α-L-arabinopyranoside, were isolated from the leaves of Gynostemma longipes C.Y.Wu. Their structures were determined by 1D- and 2D-NMR and HR-ESI-MS spectra. Compounds 1-3 exhibited moderate activity against four human cancer cell lines, A-549, HT-29, OVCAR, and MCF-7, with IC50 values ranging from 9.8 +/- 2.1 to 49.6 +/- 2.6 μM.
[Comparison of total saponin content in three wild species of Gynostemma on Mount Emei].[Pubmed: 12575131]
Analysed by TLC and spectrometry, the content of the total saponin in three wild species of Gynostemma on Mount Emei is found to be the highest in July and to be the lowest in the seedling stage. Among the three, the content of the total saponin in Gynostemma pentaphyllum is the highest, that in Gynostemma pubescens lower and that in Gynostemma longipes the lowest.
[Studies on the chemical constituents of Gynostemma longipes C.Y. Wu].[Pubmed: 11596278]
A new triterpenoid saponin named gylongiposide I was isolated from the aerial parts of Gynostemma longipes C.Y. Wu. On the basis of chemical evidence and spectral data the structure of gylongiposide I was elucidated as 19-oxo-3 beta, 20(S), 21-trihydroxydammar-24-ene-3-O-([alpha-L-rhamnopyranosy(1-->2)] [beta-D-xylpyranosyl(1-->3)]) alpha-L-arabinopyranoside (G). The known compounds were identified as gypenoside XLIX(F) and ginsenoside Rb1(A).
