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Leonurus macranthus

Leonurus macranthus

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Natural products/compounds from  Leonurus macranthus

  1. Cat.No. Product Name CAS Number COA
  2. BCN4885 Hydroxygenkwanin20243-59-8 Instructions
  3. BCN1209 Eriodictyol552-58-9 Instructions
  4. BCN4582 Isoscopoletin776-86-3 Instructions

References

Anti-inflammatory Labdane Diterpenoids from Leonurus macranthus.[Pubmed: 26348503]


Twenty new polyoxygenated labdane diterpenoids (1-20) were isolated from the aerial parts of Leonurus macranthus. Their structures were elucidated on the basis of spectroscopic and spectrometric data (1D and 2D NMR, IR, and HRESIMS). The absolute configurations of macranthin A (1) and 6-O-deacetylmacranthin A (2) were determined by single-crystal X-ray crystallographic analysis and a modified Mosher's method, respectively. Compounds 1-9, 12, 14, and 19 showed inhibition of nitric oxide production in lipopolysaccharide-activated BV-2 microglial cells with IC50 values of 10.0-63.7 μM.