Natural Products from Tinospora sagittata var. yunnanensis
Natural Products Isolated from Tinospora sagittata var. yunnanensis
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Natural Products from Tinospora sagittata var. yunnanensis
1 natural product associated with Tinospora sagittata var. yunnanensis
References
New clerodane diterpenes from Tinospora sagittata var. yunnanensis.[Pubmed: 24634023]
Four new clerodane diterpenes, namely sagittatayunnanosides A-D (1-4), were isolated from the roots of Tinospora sagittata var. yunnanensis, together with two known compounds, tinospinoside C (5) and tinospinoside E (6). The structures of the four new compounds were well elucidated by extensive analyses of the MS, IR, and 1D and 2D NMR data. The cytotoxic and antifouling activities of compounds 1-6 were evaluated.
A novel lignan glycoside with antioxidant activity from Tinospora sagittata var. yunnanensis.[Pubmed: 21942471]
A novel lignan glysocide, namely sagitiside A (1), together with two known ones, (+)-lyoniresinol-2α-O-β-D-glucopyranoside (2) and (+)-5'-methoxyisolariciresinol 3α-O-β-D-glucopyranoside (3), was isolated from the 95% ethanol extract of dry roots of Tinospora sagittata var. yunnanensis. The structure of the new compound (1) was determined based on MS, 1D and 2D NMR spectral data. Compounds 1-3 showed antioxidant activity with EC(50) values 55, 75 and 80 µM by 1,1-diphenyl-2-picryhydrazyl (DPPH) radical-scavenging assay.
[Studies on the chemical constituents from the roots of Tinospora sagittata var. yunnanensis (II)].[Pubmed: 21355194]
To study the chemical constituents from the roots of Tinospora sagittata var. yunnanensis.
A novel 18-norclerodane diterpenoid from the roots of Tinospora sagittata var. yunnanensis.[Pubmed: 21081856]
A novel 18-nor-clerodane diterpenoid named sagitone (1) was isolated from the 95% ethanol extract of dry roots of Tinospora sagittata var. yunnanensis together with the five known diterpenoids columbin (2), palmatoside C (3), fibleucin (4), tinophylloloside (5) and epitinophylloloside (6). The structure of the new compound 1 was determined based on MS, IR, 1D and 2D NMR spectral data. The compounds 1-6 did not show significant cytotoxic activity against cancer cell lines K562 and HL-60.