Ganoderic acid C2

Catalog No. BCN3036
CAS RN 103773-62-2
Molecular Weight 518.7
Molecular Formula C30H46O7
Database [PubChem]:382152825
[ChEBI]:
[PCIDB]:

Definition

Standard InChI

InChI=1S/C30H46O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21-23,32,34-35H,8-14H2,1-7H3,(H,36,37)/t15-,16-,18-,19+,21+,22+,23+,28+,29-,30+/m1/s1

Biological Activity

Ganoderic acid C2, isolated from the spores, has cytotoxicity in vitro against Meth-A and LLC cell lines.[1]
CHCl(3) extract of the fruiting body of Ganoderma lucidum was found to show inhibitory activity on human aldose reductase in vitro, and ganoderic acid C2 and ganoderenic acid A is essential in eliciting the inhibitory activity considering the much lower activity of their methyl esters.[2]
Ganoderenic acid C2 exhibits hepatoprotective activities against DL-galactosamine-induced cell damage in HL-7702 cells. [3]

Product information

English website: Ganoderic acid C2
Japanese website: Ganoderic acid C2
Chinese website: Ganoderic acid C2

References

[1] Min B S, Gao J J, Nakamura N, et al. Cheminform, 2000, 31(50):1026-33.
[2] Fatmawati S, Shimizu K, Kondo R.Planta Med, 2010, 76(15):1691-3.
[3] Liu L Y, Hui C, Chao L, et al. Fitoterapia, 2014, 98:254-9.
[4] Zhao J, Chen X, Kaishun B I. China journal of Chinese materia medica, 2009, 34(17):2220-2.