InChI=1S/C30H46O2/c1-20(19-31)9-8-10-21(2)22-13-17-30(7)24-11-12-25-27(3,4)26(32)15-16-28(25,5)23(24)14-18-29(22,30)6/h9,11,14,21-22,25,31H,8,10,12-13,15-19H2,1-7H3/b20-9+/t21-,22+,25?,28-,29-,30+/m1/s1
Ganoderol A, isolated from Ganadermalucidum, has significant anti-inflammatory activity and protection against UVA damage, thus suggesting that the compound is a candidate for the development of a suitable product to protect skin from UV-induced photoaging.[1]
Ganoderols A, the 70% MeOH extract of Ganoderma lucidum , has an inhibitory effect on angiotensin converting enzyme activity.[2]
Ganoderal A inhibits cholesterol biosynthesis via conversion of acetate or mevalonate as a precursor of cholesterol. [3]
Ganoderone A and lucialdehyde B exhibit potent inhibitory activity against herpes simplex virus.[4]
English website: Ganoderol A
Japanese website: Ganoderol A
Chinese website: Ganoderol A
[1] Jin F, Zhao H, Yuan X, et al. Trop J Pharm Res, 2015, 14(3):412-21.
[2] Morigiwa A, Kitabatake K, Fujimoto Y, et al. Chem Pharm Bul, 1986, 34(7):3025-8.
[3] Hajjaj H, Macé C, Roberts M, et al. Appl Environ Microb, 2005, 71(7):3653-8.
[4] Niedermeyer T H, Lindequist U, Mentel R, et al. Planta Med, 2005, 68(12):1728-31.
[5] Zhao J, Zhang X, Li S, et al. J Sep Sci, 2006, 29(17):2609-15.
