Lobetyolin

Catalog No.	BCN5894
CAS RN	136085-37-5
Molecular Weight	396.43
Molecular Formula	C20H28O8
Database	[PubChem]:382155315 [ChEBI]: [PCIDB]:30684

Definition

Standard InChI

InChI=1S/C20H28O8/c1-2-3-4-5-7-10-14(23)15(11-8-6-9-12-21)27-20-19(26)18(25)17(24)16(13-22)28-20/h2-3,8,11,14-26H,6,9,12-13H2,1H3/b3-2+,11-8+/t14?,15?,16-,17-,18+,19-,20-/m1/s1

Biological Activity

Lobetyolin has a protective role in gastric mucosa injury,and the mechanism may be relate to the increase in level of 6-K-PGF1αand the inhibition the excretion of gastric acid and EGF.[1]
Lobetyolin, lobetyol, and methyl linoleate inhibit the gene expression of MUC5AC mucin induced by PMA, however lobetyolin did not affect PMA-induced MUC5AC mucin production. [2]

Product information

English website: Lobetyolin
Japanese website: Lobetyolin
Chinese website: Lobetyolin

References

[1] Song D, Wang Z T, Long-Yun L I. Journal of Emergency in Traditional Chinese Medicine, 2008, 17(7):963-4.
[2] Yoon Y P, Ryu J, Park S H, et al. Tuberculosis & Respiratory Diseases, 2014, 77(5):203-8.
[3] Song D, Cheng X M, Long-Yun L I, et al.China Journal of Chinese Materia Medica, 2008, 33(17):2133-5.