Emodin-8-beta-D-glucoside

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Catalog No.	BCN6329
CAS RN	23313-21-5
Molecular Weight	432.41
Molecular Formula	C21H20O10
Database	[PubChem]:382158800 [ChEBI]: [PCIDB]:32938

Definition

Standard InChI

InChI=1S/C21H20O10/c1-7-2-9-14(11(24)3-7)18(27)15-10(16(9)25)4-8(23)5-12(15)30-21-20(29)19(28)17(26)13(6-22)31-21/h2-5,13,17,19-24,26,28-29H,6H2,1H3

Biological Activity

Emodin-8-O-beta-D-glucoside extracted from the traditional Chinese medicinal herb Polygonum cuspidatum Sieb. et Zucc is widely used to treat acute hepatitis possibly by antioxidative mechanisms; it is able to provide neuroprotection against cerebral ischemia-reperfused injury and glutamate induced neuronal damage through exerting antioxidative effects and inhibiting glutamate neurotoxicity.[1]
Emodin-8-O-β-D-glucoside can promote proliferation and differentiation of osteoblastic MC3T3-E1 cells.[2]

Product information

English website: Emodin-8-beta-D-glucoside
Japanese website: Emodin-8-beta-D-glucoside
Chinese website: Emodin-8-beta-D-glucoside

References

[1] Wang C, Zhang D, Ma H, et al. Eur J Pharmacol, 2007, 577(1-3):58-63.
[2] Xiang MX, Xu Z, Su HW, et al. Molecules, 2011, 16(1):728-37.
[3] Koyama J, Morita I, Kobayashi N. J Chromatogr A, 2007, 1145(1-2):183-9.