InChI=1S/C21H20O11.ClH/c22-7-16-17(27)18(28)19(29)21(32-16)31-15-6-10-12(25)4-9(23)5-14(10)30-20(15)8-1-2-11(24)13(26)3-8;/h1-6,16-19,21-22,27-29H,7H2,(H3-,23,24,25,26);1H/t16-,17+,18+,19-,21-;/m1./s1
Cyanidin-3-O-galactoside is a flavonoid-enriched extract derived from the peel of Northern Spy apples, has neuroprotective effects, can reduce HI-induces brain injury and motor deficits by increasing the resistance of vulnerable neurons to ischemiccell death and decreasing the production of inflammatory cytokines.[1]
Cyanidin-3-O-galactoside and blueberry extracts were shown effective functions to relieve cellular injury, improve hippocampal neurons survival and inhibit the pyramidal cell layer damage; also increases SOD activity and reduces MDA content in brain tissues and plasma, and increased hippocampal phosphorylated ERK (p-ERK) expression in SAMP8 mice; thus, cyanidin-3-O-galactoside and blueberry extracts supplementation can improve spatial memory and regulates hippocampal ERK expression in senescence-accelerated mice.[2]
Cyanidin-3-O-galactoside has antioxidant activity in the reduction of the stable DPPH radical and in the inhibition of lipid peroxidation.[3]
English website: Cyanidin-3-O-galactoside chloride
Japanese website: Cyanidin-3-O-galactoside chloride
Chinese website: Cyanidin-3-O-galactoside chloride
[1] Dunlop K E. DalSpace Home. 2012, 11.20.
[2] Tan L, Yang H P, Pang W, et al. Biomed EnvironSci, 2014, 27(3):186-96.
[3] Giomaro G, Karioti A, Bilia A R, et al. Chem Cent J, 2014, 8(1):1-10.
[4] Ha T J, Lee M H, Yu N J, et al. Food Sci Biotechnol, 2010, 19(3):821-6.
