A stilbenoid that is trans-stilbene which has been substituted by hydroxy groups at positions 2, 3, 5, and 4', and in which the hydroxy group at positon 2 has then been converted to the corresponding the β-D-glucoside.
InChI=1S/C20H22O9/c21-9-15-16(25)17(26)18(27)20(28-15)29-19-11(7-13(23)8-14(19)24)4-1-10-2-5-12(22)6-3-10/h1-8,15-18,20-27H,9H2/b4-1+/t15-,16-,17+,18-,20+/m1/s1
2,3,5,4'-Tetrahydroxyldiphenylethylene-2-O-glucoside(TSG) blocks the proliferation of PASMCs induced by PDGF-BB through arresting the cell cycle in G0 / G1 phase, indicates that TSG suppress PDGF-BB-induced PASMCs proliferation is associated with an inhibition of AKT / GSK3β signaling pathways.[1]
Stilbeneglycoside has protective effects of preconditioning in an ischemia/reperfusion model of HUVECs.[2]
Stilbene glycoside has active effect on proliferation and differentiation of rat's osteoblasts, can promote the mature of osteoblasts.[3]
English website: 2,3,5,4'-Tetrahydroxyl diphenylethylene-2-O-glucoside
Japanese website: 2,3,5,4'-Tetrahydroxyl diphenylethylene-2-O-glucoside
Chinese website: 2,3,5,4'-Tetrahydroxyl diphenylethylene-2-O-glucoside
[1] Guan W J, Xu C. J Med Res, 2015, 44 (06): 122-6.
[2]Li-ping, Zhang-ping, LIAO, et al. Acta Pharmacol Sin, 2010, 31(4):405-12.
[3] Jiwei W U. Hebei MedJ, 2014(05):654-6.
[4] Gang D , An S F, Liu CY. West China J Pharm Sci, 2003, 17(4):297-9.
