Natural product based Anti-aging and prolonging life therapy
A pharmaceutical mixture increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), reduces INSR protein levels and enhances lifespan via down regulation of its target gene
An investigation from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str. Bonn, Germany; and Institute for Genetics and CECAD Research Center, University of Cologne, Joseph-Stelzmann Str. Cologne, Germany demonstrates that The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover. This study paper was published, in the April 20th, 2017 issue of the journal Cell , by Prof. Hoppe T,Tawo R and others.
Prof. Hoppe T