Results of development of geranylin acylated anthocyanins

We have been specialized in developing natural products active ingredients for many years, among which we have developed many special anthocyanins natural pigment ingredients. Anthocyanidins, also known as flower pigments, are water-soluble natural pigments widely found in plants, which are colorful glycosides obtained by hydrolysis of Anthocyains. There are six common species in plants, namely geranium pigment (Pg), cornflower pigment (Cy), delphinium pigment (Dp), peony pigment (Pn), petunia pigment (Pt) and mallow pigment (Mv).
         Geranium pigment, also known as anemone. It promotes blood circulation and makes pale skin more rosy after use. Geranium essential oil has a good hypnotic effect. Over 200 anthocyanidins have been identified to date, including delphinidin, cyanidin, anemone, peonidin, and malvidin. Anthocyanidin glycosides are involved in anti-inflammatory, anti-microbial and cholesterol-lowering effects, especially with antioxidant activity. Anthocyanidins, anthocyanidin glycosides or black rice extracts containing anthocyanidins and anthocyanidin glycosides inhibit the aggregation of eosinophils in tissues and consequently have an inhibitory effect on allergic inflammation, thus allowing the above substances to be used effectively in the prevention or treatment of allergic diseases related to inflammation and eosinophil aggregation, said allergic diseases such as allergic rhinitis, allergic conjunctivitis, asthma, chronic obstructive pulmonary disease, atopic atopic dermatitis, allergic diarrhea, etc.
        Grass Source has conducted in-depth research and development on these substances, and this time, we have especially developed and isolated acylated geranosides, and obtained more than ten acylated anthocyanin monomer compounds, and after NMR structure identification and HPLC purity analysis, the purity of the isolated anthocyanins is above 97%. The following compounds were included.
1、Pelargonidin 3-O-[6''-O-(E)caffeoylsophoroside]-5-O-glucoside, CAS: 361342-09-8 .

2、Pelargonidin 3-O-[6-O-(E)-caffeoylsophoroside]-5-O-(6-O-malonyl)-β-D-glucoside, CAS：1034402-86-2 .

3、Pelargonidin 3-O-[6-O-(E)-caffeoyl-2-O-{6-O-(E)-caffeoyl-β-D-glucoside}-β-D-glucoside]-5-glucoside, CAS：184882-07-3 .

4、Pelargonidin 3-O-[6-O-(E)-caffeoyl-2-O-{6-O-(E)-caffeoyl-β-D-glucoside}-β-D-glucoside]-5-O-(6-O-malonyl)-β-D-glucoside, CAS：1333206-55-5.

5、Pelargonidin 3-O-[6-O-(E)-feruloyl-2-O-β-D-glucoside}-β-D-glucoside]-5-O-(6-O-malonyl)-β-D-glucoside, CAS：1034402-86-2.

6、Pelargonidin 3-O-[6-O-(E)-feruloyl-2-O-{6-O-(E)-caffeoyl-β-D-glucoside}-β-D-glucoside]-5-O-(6-O-malonyl)-β-D-glucoside, CAS：1333206-58-8.

7、Pelargonidin 3-O-[6-O-(E)-feruloyl-2-O-{6-O-(E)-feruloyl-β-D-glucoside}-β-D-glucoside]-5-O-(6-O-malonyl)-β-D-glucoside, CAS: 925673-36-5.

8. Pelargonidin 3-O-[6-O-(E)-feruloyl-2-O-{6-O-(E)-p-coumaroyl-β-D-glucoside}-β-D-glucoside]-5-O-(6-O-malonyl)-β-D-glucoside, CAS: 1333206-60-2.

In addition to the above compounds, some more are under continuous isolation and identification, and the results will be released later.