Trichosanthes kirilowii
Trichosanthes kirilowii
Trichosanthes kirilowii is a flowering plant in the family Cucurbitaceae found particularly in China. It is one of the 50 fundamental herbs used in traditional Chinese medicine. The plant is a source of the toxic anti-HIV type I ribosome-inactiving lectin trichosanthin. It is found that the anti-tumor components isolated from the extract of trichosanthes (EOT) are cucurbitacin D and dihydrocucurbitacin D, and suggest that cucurbitacin D induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells. Trichosanthes kirilowii tuber is a traditional medicine which exhibits various medicinal effects including antidiabetic and anticancer activities in several cancer cells. Recently, it was reported that Cucurbitacin D (CuD) isolated from Trichosanthes kirilowii also induces apoptosis in several cancer cells. Constitutive signal transducer and activator of transcription 3 (STAT3), which is an oncogenic transcription factor, is often observed in many human malignant tumor, including breast cancer.
Products from Trichosanthes kirilowii
- Cat.No. Product Name CAS Number COA
- BCN1206 Palmitic acid 57-10-3 PDF
- BCN5564 alpha-Spinasterol 481-18-5 PDF
- BCN1120 alpha-Spinasterol glucoside 1745-36-4 PDF
- BCN5510 alpha-Spinasterol acetate 4651-46-1 PDF
- BCN2717 3,29-Dibenzoyl karounitriol 873001-54-8 PDF
- BCN2704 Karounidiol 118117-31-0 PDF
- BCN5531 Daucosterol 474-58-8 PDF
- BCN1015 Beta-Sitosterol 83-46-5 PDF
- BCN4376 Stigmasterol 83-48-7 PDF
- BCN1259 D-(+)-Glucose 50-99-7 PDF
- BCN5989 Fumaric acid 110-17-8 PDF
- BCN5890 Succinic acid 110-15-6 PDF
- BCN4090 Uridine 58-96-8 PDF
- BCN5103 Bryonolic acid 24480-45-3 PDF
- BCN5919 Cucurbitacin B 6199-67-3 PDF
- BCN1684 Rutin 153-18-4 PDF
- BCN5788 Cosmosiin 578-74-5 PDF
- BCN5328 Diosmetin-7-O-beta-D-glucopyranoside 20126-59-4 PDF
- BCN2356 Diosmetin 520-34-3 PDF
- BCN5658 Apigenin 520-36-5 PDF
- BCN5600 Luteolin 491-70-3 PDF
- BCN5601 Chrysoeriol 491-71-4 PDF
- BCN3796 Chrysoeriol-7-O-glucoside 19993-32-9 PDF
- BCN6105 Vanillic acid 121-34-6 PDF