Alatusol DCAS# 1578237-42-9 |
Quality Control & MSDS
Package In Stock
Number of papers citing our products
| Cas No. | 1578237-42-9 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Oil |
| Formula | C11H16O5 | M.Wt | 228.27 |
| Type of Compound | Phenylpropanoid | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Alatusol D Dilution Calculator
Alatusol D Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.3808 mL | 21.9039 mL | 43.8078 mL | 87.6155 mL | 109.5194 mL |
| 5 mM | 0.8762 mL | 4.3808 mL | 8.7616 mL | 17.5231 mL | 21.9039 mL |
| 10 mM | 0.4381 mL | 2.1904 mL | 4.3808 mL | 8.7616 mL | 10.9519 mL |
| 50 mM | 0.0876 mL | 0.4381 mL | 0.8762 mL | 1.7523 mL | 2.1904 mL |
| 100 mM | 0.0438 mL | 0.219 mL | 0.4381 mL | 0.8762 mL | 1.0952 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Phenolic Constituents from Platycodon grandiflorum Root and Their Anti-Inflammatory Activity.[Pubmed:34361683]
Molecules. 2021 Jul 27;26(15):4530.
Six lignols (1-6), including two new compounds (+)-(7R,8R)-palmitoyl Alatusol D (1) and (+)-(7R,8R)-linoleyl Alatusol D (2), along with four phenolics (7-10), a neolignan (11), three alkyl aryl ether-type lignans (12-14), two furofuran-type lignans (15-16), three benzofuran-type lignans (17-19), a tetrahydrofuran-type lignan (20), and a dibenzylbutane-type lignan (21) were isolated from the ethyl acetate-soluble fraction of the methanol extract of Platycodon grandiflorum (Jacq.) A. DC. root. The chemical structures of the obtained compounds were elucidated via high-resolution mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy analyses. The obtained spectroscopic data agreed well with literature. Among the isolated compounds, eighteen (1-7 and 11-21) were isolated from P. grandiflorum and the Campanulaceae family for the first time. This is the first report on lignol and lignan components of P. grandiflorum. The anti-inflammatory effects of the isolated compounds were examined in terms of their ability to inhibit the production of pro-inflammatory cytokines IL-6, IL-12 p40, and TNF-alpha in lipopolysaccharide-stimulated murine RAW264.7 macrophage cells. Nine compounds (4-6, 12, and 15-19) exhibited inhibitory effects on IL-12 p40 production, eleven compounds (1-6, 12, 15-17, and 19) exhibited inhibitory activity on IL-6 production, and eleven compounds (1-6 and 15-19) exhibited inhibitory effects against TNF-alpha. These results warrant further investigation into the potential anti-inflammatory activity and general benefits of the phenolic constituents of P. grandiflorum root.
Two pairs of phenylpropanoid enantiomers from the leaves of Eucommia ulmoides.[Pubmed:29996684]
J Asian Nat Prod Res. 2018 Nov;20(11):1045-1054.
Two pairs of phenylpropanoid enantiomers, (+)-(7S,8S)-Alatusol D (1a), (-)-(7R,8R)-Alatusol D (1b), (-)-(7S,8R)-Alatusol D (2a) and (+)-(7R,8S)-Alatusol D (2b) were isolated from the leaves of Eucommia ulmoides Oliver. Among them, 1a and 2b were firstly obtained by chiral enantiomeric resolution. Their structures were elucidated based on extensive spectroscopic analysis and the induced CD (ICD) spectrum caused by adding Mo(2)(AcO)(4) in DMSO. All compounds were tested on Hep G2 tumor cell lines. However, none of the compounds showed potential cytotoxic activity against Hep G2 in vitro.
