Aurora kinase A (AURKA), Recombinant ProteinCatalog# BCP26666 |
| Product Name | Aurora kinase A (AURKA), Recombinant Protein | ||
| Full Product Name | Aurora kinase A, 1-403aa, Human, His tag, E Coli | ||
| Product Synonym Names | Serine/threonine-protein kinase 6; Aurora-A; AIK; ARK1; AuRA; BTAK; STK15; STK6; Aurora kinase A; AuRKA; Serine/threonine-protein kinase 6 Aurora 2; Aurora A; aurora kinase A; IAK; Serine/threonine kinase 15. | ||
| Product Gene Name | AURKA recombinant protein | ||
| Research Use Only | For Research Use Only. Not for use in diagnostic procedures. | ||
| Sequence | MGSSHHHHHH SSGLVPRGSH MDRSKENCIS GPVKATAPVG GPKRVLVTQQ FPCQNPLPVN SGQAQRVLCP SNSSQRIPLQ AQKLVSSHKP VQNQKQKQLQ ATSVPHPVSR PLNNTQKSKQ PLPSAPENNP EEELASKQKN EESKKRQWAL EDFEIGRPLG KGKFGNVYLA REKQSKFILA LKVLFKAQLE KAGVEHQLRR EVEIQSHLRH PNILRLYGYF HDATRVYLIL EYAPLGTVYR ELQKLSKFDE QRTATYITEL ANALSYCHSK RVIHRDIKPE NLLLGSAGEL KIADFGWSVH APSSRRTTLC GTLDYLPPEM IEGRMHDEKV DLWSLGVLCY EFLVGKPPFE ANTYQETYKR ISRVEFTFPD FVTEGARDLI SRLLKHNPSQ RPMLREVLEH PWITANSSKP SNCQNKESAS KQS | ||
| OMIM | D84212 mRNA | ||
| 3D Structure | ModBase 3D Structure for O14965 | ||
| Host | E Coli | ||
| Purity/Purification | > 95% by SDS-PAGE | ||
| Form/Format | Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 0.5mM DTT, 100mM NaCl, 0.1mM EDTA, 0.1mM EGTA, 0.1mM PMSF, 20% glycerol. | ||
| Concentration | 0.5 mg/ml (determined by Bradford assay) (lot specific) | ||
| Antigen Species | Human | ||
| Tag Information | His-tag | ||
| Preparation and Storage | Can be stored at 4 degree C short term (1-2 weeks).For long term storage, aliquot and store at -20 degree C or -70 degree C.Avoid repeated freezing and thawing cycles. | ||
| Other Notes | Small volumes of AURKA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. | ||
| Related Product Information for AURKA recombinant protein | Aurora Kinase A is a member of a family of mitotic serine/threonine kinases. It is implicated with important processes during mitosis and meiosis whose proper function is integral for healthy cell proliferation. Aurora kinase A is highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also this protein plays a crucial role in tumourigenesis and is overexpressed in many kinds of cancers. Recombinant human Aurora-A fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography. | ||
| Product Categories/Family for AURKA recombinant protein | Cell Cycle | ||
| Applications Tested/Suitable for AURKA recombinant protein | SDS-PAGE | ||
| NCBI GI # | 38327562 | ||
| NCBI GeneID | 6790 | ||
| NCBI Accession # | NP_003591 | ||
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