Jagged-1 (JAG1), Recombinant ProteinCatalog# BCP31911 |
| Product Name | Jagged-1 (JAG1), Recombinant Protein | ||
| Full Product Name | Recombinant Human Jagged-1 Protein | ||
| Product Synonym Names | Protein jagged-1 I; Jagged-1; JAGL1; HJ1; JAG1 and CD339 | ||
| Product Gene Name | JAG1 recombinant protein | ||
| Research Use Only | For Research Use Only. Not for use in diagnostic procedures. | ||
| 3D Structure | ModBase 3D Structure for P78504 | ||
| Host | Human Cells | ||
| Purity/Purification | >90% as determined by reducing SDS-PAGE. | ||
| Form/Format | Lyophilized from a 0.2 mum filtered solution of PBS, pH 7.4. | ||
| Species | Human | ||
| Endotoxin | <1.0 EU per ug as determined by LAL test. | ||
| Fragment | Gln34-Ser1046 | ||
| Fusion Tag | C-Fc | ||
| Activity | Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells.The ED50 for this effect is typically 4-20 mug/mL. | ||
| Preparation and Storage | Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.Aliquots of reconstituted samples are stable at < -20 degree C for 3 months. | ||
| ISO Certification | Manufactured in an ISO 9001:2015 Certified Laboratory. | ||
| Other Notes | Small volumes of JAG1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. | ||
| Related Product Information for JAG1 recombinant protein | Protein Construction: Recombinant Human jagged-1 is produced by our Mammalian expression system and the target gene encoding Gln34-Ser1046 is expressed with a Fc tag at the C-terminus.Background: Protein jagged-1 I, also known as Jagged-1, JAGL1, HJ1, JAG1 and CD339, is a single-pass type I membrane protein. JAG1 contains one DSL domain and sixteen EGF-like domain. JAG1 acts as a ligand for multiple Notch receptors and is involved in the mediation of Notch signaling. JAG1 may participate in early and late stages of mammalian cardiovascular development, JAG1 inhibits myoblast differentiation and enhances fibroblast growth factor-induced angiogenesis. Defects in JAG1 are the cause of Alagille syndrome type 1, which is autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations. | ||
| NCBI GI # | 4557679 | ||
| NCBI GeneID | 182 | ||
| NCBI Accession # | NP_000205.1 | ||
Jagged-1 (JAG1), Recombinant Protein buy Jagged-1 (JAG1), Recombinant Protein , Jagged-1 (JAG1), Recombinant Protein supplier , purchase Jagged-1 (JAG1), Recombinant Protein , Jagged-1 (JAG1), Recombinant Protein cost , Jagged-1 (JAG1), Recombinant Protein manufacturer , order Jagged-1 (JAG1), Recombinant Protein , high purity Jagged-1 (JAG1), Recombinant Protein
