Leptin, Recombinant ProteinCatalog# BCP32715 |
Product Name | Leptin, Recombinant Protein | ||
Full Product Name | Human Leptin | ||
Product Synonym Names | Recombinant Human Leptin | ||
Product Gene Name | LEP recombinant protein | ||
Research Use Only | For Research Use Only. Not for use in diagnostic procedures. | ||
Sequence | MVPIQKVQD DTKTLIKTI VTRINDISH TQSVSSKQK VTGLDFIPG LHPILTLSK MDQTLAVYQ QILTSMPSR NVIQISNDL ENLRDLLHV LAFSKSCHL PWASGLETL DSLGGVLEA SGYSTEVVA LSRLQGSLQ DMLWQLDLS PGC | ||
OMIM | gene 614962 | ||
3D Structure | ModBase 3D Structure for P41159 | ||
Host | E Coli | ||
Species Reactivity | Species Reactivity: HumanCross Reactivity: Chicken, Monkey, Mouse, Rat | ||
Purity/Purification | Above 98% as determined by SDS-PAGE Analysis. | ||
Biological Activity | Human Leptin is biologically active in the ob/ob mouse obesity model. The ob/ob mice were treated via intraperitoneal injection once daily at a dose of 5 ug Leptin/gm of body weight for 7 days. Significant effects on bo | ||
Preparation and Storage | At -20 degree C | ||
Other Notes | Small volumes of LEP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. | ||
Related Product Information for LEP recombinant protein | Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant human Leptin is a 16.0 kDa protein containing 147 amino acid residues. | ||
Product Categories/Family for LEP recombinant protein | Apoptosis; Angiogenesis; Inflammation; Metabolic Regulation and Diabetes | ||
NCBI GI # | 730218 | ||
NCBI GeneID | 3952 | ||
NCBI Accession # | P41159.1 |
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