MBL/MBL2, Recombinant ProteinCatalog# BCP34001 |
| Product Name | MBL/MBL2, Recombinant Protein | ||
| Full Product Name | Human CellExp MBL/MBL2; human recombinant | ||
| Product Synonym Names | MBL; MBL2; MBP1; MBP-C; Collectin-1; COLEC1; HSMBPC; MBL2D; MBPD; Mannose binding Lectin | ||
| Product Gene Name | MBL recombinant protein | ||
| Product Synonym Gene Name | MBL2 | ||
| Research Use Only | For Research Use Only. Not for use in diagnostic procedures. | ||
| OMIM | X15422 mRNA | ||
| 3D Structure | ModBase 3D Structure for P11226 | ||
| Host | HEK 293 cellsSource: Human | ||
| Purity/Purification | >=95% | ||
| Form/Format | Lyophilized from 0.22 mum filtered solution in PBS; pH 7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization. | ||
| Tag Information | This protein is fused with 6× His tag at the C-terminus. The predicted N-terminus is Glu 21. DTT-reduced Protein migrates as 30-33 kDa. | ||
| Endotoxin Level | < 1.0 EU per mug of the protein by the LAL method. | ||
| Biological Activity | Measured by its ability to bind with Mannan in a functional ELISA. | ||
| Results | Measured by its ability to bind with Mannan in a functional ELISA. | ||
| Reconstitution | Centrifuge the vial prior to opening. Reconstitute in PBS; pH 7.4. Do not vortex. | ||
| Preparation and Storage | Store at -20 degree C for 12 months.Centrifuge the vial prior to opening. | ||
| Other Notes | Small volumes of MBL recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. | ||
| Related Product Information for MBL recombinant protein | Mannose-binding lectin (MBL) is also known as mannose-binding protein; mannan-binding protein (MBP); Mannose-binding protein C; Collectin-1 (COLEC1); MBL2; which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa); built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose; fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA. | ||
| Applications Tested/Suitable for MBL recombinant protein | SDS-PAGE | ||
| NCBI GI # | 4557739 | ||
| NCBI GeneID | 4153 | ||
| NCBI Accession # | NP_000233.1 | ||
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