OtosenineCAS# 16958-29-5 |
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| Cas No. | 16958-29-5 | SDF | Download SDF |
| PubChem ID | 6438142 | Appearance | Powder |
| Formula | C19H27NO7 | M.Wt | 381.42 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1R,3'S,4S,6R,7R,11Z)-7-hydroxy-3',6,7,14-tetramethylspiro[2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-4,2'-oxirane]-3,8,17-trione | ||
| SMILES | CC1CC2(C(O2)C)C(=O)OC3CCN(CC=C(C3=O)COC(=O)C1(C)O)C | ||
| Standard InChIKey | CZQLULNMKQAIQL-GZSSMBGUSA-N | ||
| Standard InChI | InChI=1S/C19H27NO7/c1-11-9-19(12(2)27-19)17(23)26-14-6-8-20(4)7-5-13(15(14)21)10-25-16(22)18(11,3)24/h5,11-12,14,24H,6-10H2,1-4H3/b13-5-/t11-,12+,14-,18-,19+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. D-Otocenine elicites low toxicity, it shows spasmolytic properties . |
Otosenine Dilution Calculator
Otosenine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6218 mL | 13.1089 mL | 26.2178 mL | 52.4356 mL | 65.5445 mL |
| 5 mM | 0.5244 mL | 2.6218 mL | 5.2436 mL | 10.4871 mL | 13.1089 mL |
| 10 mM | 0.2622 mL | 1.3109 mL | 2.6218 mL | 5.2436 mL | 6.5545 mL |
| 50 mM | 0.0524 mL | 0.2622 mL | 0.5244 mL | 1.0487 mL | 1.3109 mL |
| 100 mM | 0.0262 mL | 0.1311 mL | 0.2622 mL | 0.5244 mL | 0.6554 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Spasmolytic properties of pyrrolizidine alkaloids].[Pubmed:488324]
Farmakol Toksikol. 1979 Sep-Oct;42(5):509-11.
Acute toxicity, spasmolytic and hypotensive properties of the alkaloids senecionine, d-otocenine and floridanin isolated from Senecio Erraticum L. were studied. D-otocenine and floridanin elicited low toxicity, while senecionine and d-Otosenine showed spasmolytic and floridanin predominantly hypotensive properties.
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