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Protostemotinine

CAS# 169534-85-4

Protostemotinine

2D Structure

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3D structure

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Protostemotinine

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Chemical Properties of Protostemotinine

Cas No. 169534-85-4 SDF Download SDF
PubChem ID 53343513 Appearance White crystalline powder
Formula C23H29NO6 M.Wt 415.48
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1CC(OC1=O)C2CCC34N2CCCCC3=C(C(=O)C45C(=C(C(=O)O5)C)OC)C
Standard InChIKey SKYPPFSYUDCEQR-NMXNWEJOSA-N
Standard InChI InChI=1S/C23H29NO6/c1-12-11-17(29-20(12)26)16-8-9-22-15(7-5-6-10-24(16)22)13(2)18(25)23(22)19(28-4)14(3)21(27)30-23/h12,16-17H,5-11H2,1-4H3/t12-,16-,17-,22-,23+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Protostemotinine

The roots of Stemona japonica

Biological Activity of Protostemotinine

DescriptionProtostemotinine is a natural product from Stemona japonica.

Protocol of Protostemotinine

Structure Identification
Journal of China Pharmaceutical University, 2007,38 (6):499-501.

Chemical constituents of the roots of wild Stemona sessilifolia.[Reference: WebLink]

To study the chemical constituents of the roots of wild Stemona sessilifolia (Miq.) Miq. collected in Baohua Mountain, Jurong City, Jiangsu Province.
METHODS AND RESULTS:
The roots of wild S. sessilifolia were extracted with 75 % EtOH and partitioned by CHCl3 and n-BuOH. The compounds were separated and purified by column chromatography with silica gel and macroporous resin, and their structures were identified by spectroscopic analyses. Ten compounds were isolated from the root of S. sessilifolia in this study, i. e., one new dihydrophenanthrene named 7-methoxy-3-methyl-2,5-dihydroxy- 9, 10-dihydrophenanthrene (1), and 9 of known compounds: stilbostemin D (2), protostemonine (3), Protostemotinine (4), stemospironine (5), (-)-syringaresinol-4-O-β-D-glucopyranoside (6), benzoic acid (7), vanillic acid (8), daucosterol (9), and stigmasterol (10).
CONCLUSIONS:
Compound 1 is a new compound, compound 6 is isolated from the genus for the first time, and compounds 7 - 10 are isolated from the species for the first time.

Protostemotinine Dilution Calculator

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Protostemotinine Molarity Calculator

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Preparing Stock Solutions of Protostemotinine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4069 mL 12.0343 mL 24.0685 mL 48.1371 mL 60.1714 mL
5 mM 0.4814 mL 2.4069 mL 4.8137 mL 9.6274 mL 12.0343 mL
10 mM 0.2407 mL 1.2034 mL 2.4069 mL 4.8137 mL 6.0171 mL
50 mM 0.0481 mL 0.2407 mL 0.4814 mL 0.9627 mL 1.2034 mL
100 mM 0.0241 mL 0.1203 mL 0.2407 mL 0.4814 mL 0.6017 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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