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Procumboside A

CAS# 850894-16-5

Procumboside A

Catalog No. BCX0467----Order now to get a substantial discount!

Product Name & Size Price Stock
Procumboside A: 5mg $828 In Stock
Procumboside A: 10mg Please Inquire In Stock
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Quality Control of Procumboside A

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Chemical structure

Procumboside A

Chemical Properties of Procumboside A

Cas No. 850894-16-5 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C19H20O9 M.Wt 392.39
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Procumboside A Dilution Calculator

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Procumboside A Molarity Calculator

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Preparing Stock Solutions of Procumboside A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5485 mL 12.7424 mL 25.4848 mL 50.9697 mL 63.7121 mL
5 mM 0.5097 mL 2.5485 mL 5.097 mL 10.1939 mL 12.7424 mL
10 mM 0.2548 mL 1.2742 mL 2.5485 mL 5.097 mL 6.3712 mL
50 mM 0.051 mL 0.2548 mL 0.5097 mL 1.0194 mL 1.2742 mL
100 mM 0.0255 mL 0.1274 mL 0.2548 mL 0.5097 mL 0.6371 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Procumboside A

Antiinflammatory effects and chemical constituents of Veronicastrum axillare.[Pubmed:24817590]

Phytother Res. 2014 Oct;28(10):1561-6.

Our study aims to ascertain the antiinflammatory activity of Veronicastrum axillare and characterize the bioactive constituents. Antiinflammatory activity of the total extract and different fractions from V. axillare was investigated by employing the xylene-induced mouse ear edema model. As a result, the ethyl acetate (EtOAc) fraction showed the highest antiinflammatory activity in vivo. From the EtOAc fraction and the inactive dichloromethane fraction, a total of five new compounds, axillasides A-C and axillactones A and B, together with four known compounds, Procumboside A, buergeriside C1 , indole-3-carboxylic acid and apigenin, were isolated and identified. Their structures were elucidated on the basis of spectroscopic analysis and by comparison of their nuclear magnetic resonance data with those reported in the literature. Procumboside A, a major constituent in EtOAc fraction, showed significant antiinflammatory activity in vivo. Further studies revealed that Procumboside A was a potent COX-2 inhibitor, significantly reducing the COX-2 protein level in lipopolysaccharide-stimulated RAW 264.7 macrophages.

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