Ribonucleotide Reductase
Ribonucleotide Reductases (RNRs) are iron-dependent reductase enzymes that catalyze the rate-limiting step of de novo deoxynucleotide (dNTP) synthesis. Ribonucleotide reductase is composed of two subunits; RNR1 and RNR2, which form heterodimeric tetramers.
Products for Ribonucleotide Reductase
- Cat.No. Product Name Information/Activity
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BCC1173
Cladribine
Cladribine is an adenosine deaminase inhibitor used to treat hairy cell leukemia and multiple sclerosis.
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BCC1076
Gemcitabine HCl
Gemcitabine Hydrochloride (LY 188011 hydrochloride) is a DNA synthesis inhibitor which inhibits the growth of BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells with IC50s of 37.6, 42.9, 92.7, 89.3 and 131.4 nM, respectively.
