Bruton's Tyrosine Kinase
Bruton's Tyrosine Kinase (BTK) is member of the Tec family that is critically important for the growth, differentiation and activation of myeloid-, mast- and B-cells. BTK is initially activated by membrane localization which is stimulated by the generation of PIP3.
Products for Bruton's Tyrosine Kinase
- Cat.No. Product Name Information/Activity
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BCC4100
PCI 29732
PCI 29732 is a selective and irreversible Btk inhibitor with IC50 of 8.2 nM in a FRET based biochemical enzymology assay.
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BCC6268
PF 06465469
PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2 nM.
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BCC7051
(-)-Terreic acid
Selective inhibitor of BTK
