ITK
ITK (IL-2-inducible T-cell kinase) is a member of the Tec family of nonreceptor tyrosine kinases that are critically important for the growth, differentiation and activation of myeloid-, mast- and B-cells. ITK has a critical role in T-cell growth, signaling and function.
Products for ITK
- Cat.No. Product Name Information/Activity
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BCC1424
BMS-509744
BMS-509744 is a potent, selective and ATP competitive Itk inhibitor with an IC50 of 19 nM.
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BCC6268
PF 06465469
PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2 nM.
