P21-activated Kinases

P21-activated kinases (PAKs), EC 2.7.11.1, are serine/threonine kinases that are effector proteins for the Rho GTPases Cdc42 and Rac. Six PAK isoforms have been identified to date, which can be split into group A (PAK1, PAK2, PAK3) and group B (PAK4, PAK5, PAK6).

Products for P21-activated Kinases

  1. Cat.No. Product Name Information/Activity
  2. BCC4978 IPA-3 IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, and shows no inhibition to group II PAKs (PAKs 4-6). IPA-3 chemical structure
  3. BCC6128 PIR 3.5 6088-51-3 PIR 3.5 chemical structure

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