Retinoic Acid Receptor
Retinoic acid receptors (RARs) are nuclear hormone receptors of the NR1B class, which function as heterodimers with retinoid X receptors (RXRs). There are three distinct RAR subtypes: RARα , present in most tissue types; and RARβ and RARγ , with more selective expression.
Products for Retinoic Acid Receptor
- Cat.No. Product Name Information/Activity
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BCC7848
AC 261066
AC-261066 is a potent, orally available and isoform-selective retinoic acid beta2 (RARbeta2) receptor agonist, with a pEC50 of 8.0.
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BCC7359
AC 55649
AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.
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BCC5373
AM580
AM580 is a selective RARα agonist with IC50 and EC50 of 8 nM and 0.36 nM, respectively.
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BCC1983
Tamibarotene
Tamibarotene is a retinoic acid receptor α/β (RARα/β) agonist, showing high selectivity over RARγ.
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BCC6031
BMS 753
215307-86-1
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BCC7680
BMS 961
185629-22-5
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BCC7406
CD 1530
107430-66-0
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BCC6071
CD 2314
170355-37-0
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BCC7110
CD 437
CD437 is a selective Retinoic Acid Receptor γ (RARγ) agonist.
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BCC7241
Ch 55
Ch55 is a potent synthetic retinoid. Ch55 binds to RAR-α and RAR-β receptors with high affinity. Ch55 displays low affinity for cellular retinoic acid binding protein (CRABP). Ch55 is a potent inducer of the differentiation of HL60 cells with an EC50 of 200 nM. Ch55 can be used for cancer research.
