Telomerase

Telomerase is a ribonucleoprotein composed of an internal telomerase RNA template (TERC) and the enzyme, telomerase reverse transcriptase (TERT). Telomerase adds repeat sequences of DNA (TTAGGG) to the end of chromosomes - multiple repeats of this are a 'telomere'.

Products for Telomerase

  1. Cat.No. Product Name Information/Activity
  2. BCC1147 BIBR 1532 BIBR 1532 is a potent, selective and non-competitive telomerase inhibitor with IC50 of 100 nM in a cell-free assay. BIBR 1532 chemical structure
  3. BCN5740 Costunolide Costunolide, a sesquiterpene lactone, exhibits anti-inflammatory and anti-oxidant properties and mediates apoptosis. Costunolide chemical structure
  4. BCC7899 TMPyP4 tosylate TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand, which inhibits the interaction between G-quadruplexes and IGF-1. TMPyP4 tosylate (TMP 1363) is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines. TMPyP4 tosylate chemical structure

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