TRPA1

The ankyrin-like receptor family (TRPA1) is a member of the transient receptor potential (TRP) superfamily of ion channels. TRPA1 is classed as a thermoTRP: a TRP channel which is gated by temperature and functions as a temperature transducer.

Products for TRPA1

  1. Cat.No. Product Name Information/Activity
  2. BCC4074 Icilin Icilin(AG 3-5) is a synthetic super-agonist of TRPM8 ion channel. Icilin chemical structure
  3. BCC6323 Optovin Optovin is a reversible photoactive TRPA1 activator; stimulates human TRPA1 channels in vitro and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM). Optovin chemical structure
  4. BCC7597 Polygodial 6754-20-7 Polygodial chemical structure
  5. BCC7967 A 967079 A-967079 is a selective TRPA1 receptor antagonist with IC50s of 67 nM and 289 nM at human and rat TRPA1 receptors, respectively, and has good penetration into the CNS. A 967079 chemical structure
  6. BCC7634 AP 18 Reversible TRPA1 channel blocker AP 18 chemical structure
  7. BCC4910 HC-030031 HC-030031 is a potent and selective TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC50s of 6.2±0.2 and 5.3±0.2 μM, respectively. HC-030031 chemical structure
  8. BCC7816 TCS 5861528 Chembridge-5861528 is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx (IC50 values are 14.3 and 18.7μM respectively). TCS 5861528 chemical structure

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