Neurotensin Receptors
Neurotensin (NT) is a brain and gastrointestinal peptide that acts on three subtypes of neurotensin receptors: the G-protein-coupled receptors NTS1 (high affinity) and NTS2 (low affinity) and the single transmembrane receptor NTS3 (Sortilin 1).
Products for Neurotensin Receptors
- Cat.No. Product Name Information/Activity
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BCC5863
JMV 449
139026-66-7
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BCC5845
Kinetensin (human)
Kinetensin is a neurotensin-like peptide isolated from pepsin-treated human plasma.
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BCC5840
Neuromedin N (rat, mouse, porcine, canine)
Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes.
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BCC5842
Neurotensin
Neurotensin, a gut tridecapeptide, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors (NTR).
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BCC5876
Xenin 8
117442-28-1
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BCC7323
SR 142948
184162-64-9
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BCC7763
SR 48692
Meclinertant (SR 48692) is a potent, selective, nonpeptide and orally active neurotensin receptor 1 (NTS1) antagonist. In human colon carcinoma (HT-29) cells, Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization with a pA2 values of 8.13. Meclinertant has anxiolytic, anti-addictive and memory-impairing effects.
