Retinoic Acid-related Orphan Receptor
Retinoic acid-related Orphan Receptors (RORs) are a family of orphan nuclear receptors that are believed to play a role in numerous physiological processes, including circadian rhythm and bone metabolism. The endogenous ligand for these receptors is not yet known.
Products for Retinoic Acid-related Orphan Receptor
- Cat.No. Product Name Information/Activity
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BCC1963
SR1078
SR1078 is an agonist of retinoic acid receptor-related orphan receptor α/γ (RORα/RORγ).
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BCC6309
SR 1001
SR1001 is a selective RORα and RORγt inverse agonist with Kis 172 and 111 nM, respectively.
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BCC6310
SR 2211
SR2211 is a potent, selective synthetic RORγ modulator and functions as an inverse agonist, with a Ki of 105 nM and an
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BCN2185
Retinoic acid
Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM.
