Pain and Inflammation Research

Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.

Pain and Inflammation Research Products Areas

Products for Pain and Inflammation Research - Page 97

Cat.No. Product Name Information/Activity
BCC5801 GR 73632 GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals.
BCC5923 Hemokinin 1 (human) 491851-53-7
BCC5774 Hemokinin 1 (mouse) Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively.
BCC6960 [Sar9,Met(O2)11]-Substance P [Sar9,Met(O2)11]-Substance P is a tachykinin NK1 receptor selective agonist.
BCC7509 CP 96345 132746-60-2
BCC6016 CP 99994 dihydrochloride 145148-39-6
BCC5907 FK 888 138449-07-7
BCC5802 GR 82334 129623-01-4
BCC7840 L 760735 188923-01-5
BCC6821 L-732,138 L-732138 is a selective, potent and competitive neurokinin-1 (NK-1) receptor antagonist with an IC50 of 2.3 nM. L-732138 has 200-fold more potent in cloned human NK-1 receptors than cloned rat NK-1 receptors, and has > 1000-fold more potent than human NK-2 and NK-3 receptors. L-732138 can reduce hyperalgesia and has antitumor action.