Histamine H1 Receptor
Histamine H1 receptors are Gα q/11-protein-coupled receptors that mediate allergic responses. These receptors are expressed in a wide variety of tissues including the gastrointestinal tract, CNS, airway and vascular smooth muscle cells and endothelial cells.
Products for Histamine H1 Receptor - Page 2
- Cat.No. Product Name Information/Activity
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BCC1262
Loratadine
Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity.
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BCC6740
Mepyramine maleate
Mepyramine maleate, a first generation antihistamine, is an antagonist of histamine H1 receptor, with Kds of 0.8 nM, 5200 nM and >3000 nM for H1, H2, and H3 receptor, respectively, and a pKd of 9.4 for H1 receptor.
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BCC4923
Mirtazapine
Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors.
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BCC4545
Olopatadine HCl
Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis.
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BCC3866
Terfenadine
Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.
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BCC6742
trans-Triprolidine hydrochloride
550-70-9
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BCC7838
Zotepine
26615-21-4
