Chloride Channel
Chloride channels are a family of anion-selective channels involved in the regulation of the excitability of neurons, skeletal, cardiac and smooth muscle, cell volume regulation, transepithelial salt transport and the acidification of intra- and extracellular compartments.
Products for Chloride Channel - Page 2
- Cat.No. Product Name Information/Activity
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BCC4104
GlyH-101
GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.
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BCC6711
NPPB
NPPB is a blocker of the outwardly rectifying chloride channel (ORCC).
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BCC5248
PPQ-102
PPQ-102 is a potent CFTR inhibitor which can completely inhibited CFTR chloride current with IC50 of ~90 nM.
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BCC6220
T16Ainh - A01
T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC).
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BCC7391
Talniflumate
66898-62-2
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BCC7578
KM 11060
KM11060 is a novel corrector of the F508del-CFTR trafficking defect.
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BCC7820
PG 01
PG01 is a potent CFTR Cl- channel potentiator. PG01 can correct gating defects of CFTR mutants, is effective on b>E193K
