Products for LXR
- Cat.No. Product Name Information
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BCC3983
SR-9243
SR9243 is a liver-X-receptor (LXR) inverse agonist that induces LXR-corepressor interaction.
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BCC1178
T0901317
T0901317 is a potent and selective agonist for LXR and FXR, with EC50s of 50 nM and 5 μM, respectively[1,2]. T0901317 induces its anti-proliferative and cytotoxic effects via an LXR-independent mechanism. T0901317 significantly suppresses cell proliferation and induces programmed cell death in a dose- and time-dependent manner. T0901317 can protect mice from high fat diet-induced obesity and insulin resistance.
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BCC1612
GW3965
GW3965 is a potent, selective liver X receptor (LXR) agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM, respectively.
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BCC3790
GW3965 HCl
GW3965 hydrochloride is a potent and selective liver X receptor (LXR) agonist with EC50s of 190 and 30 nM for hLXRα and hLXRβ , respectively.
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BCC7412
Fexaramine
Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity relative to natural compounds.
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BCC4273
LXR-623
LXR-623 is a brain-penetrant partial LXRα and full LXRβ agonist, with IC50s of 24 nM and 179 nM, respectively.
