Products for Caspase
- Cat.No. Product Name Information
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BCC2358
Ac-IEPD-AFC
Ac-IEPD-AFC (IEPD) is a substrate of Granzyme B.
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BCC3648
VX-765
Belnacasan (VX-765) is an orally bioactive prodrug of VRT-043198, which is a potent and selective inhibitor of IL-converting enzyme (ICE)/caspase-1 with Kis of 0.8 nM and less than 0.6 nM for caspase-1 and caspase-4, respectively. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1β and IL-18 by human PBMCs with an IC50 of ~0.7 μM.
