Products with Alpha-glucosidase inhibitors Bioactivity

Explore BioCrick products associated with Alpha-glucosidase inhibitors biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN2683	Chikusetsusaponin IV
1. Chikusetsusaponin IV might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway.
BCN2986	2'-Methoxykurarinone
2'-Methoxykurarinone has strong alpha-glucosidase inhibitory activities, with IC(50) values of 155 microM. 2'-Methoxykurarinone is a noncompetitive inhibitor of protein tyrosine phosphatase 1B, it exhibits cellular activity in the insulin signaling pathway by increasing the insulin-stimulated Akt phosphorylation level in human hepatocellular liver carcinoma HepG2 cells, suggesting its potential for new anti-insulin-resistant drug developments. 2′-Methoxykurarinone exhibits lethal activity against Trypanosoma cruzi.,the minimum lethal concentrations is 6.9 uM.
BCN3260	Chebulic acid
1. Chebulic acid at both doses (25 and 50 mg/kg) improves biochemical alterations caused by renal ischemia in diabetic rats. 2. Chebulic acid has effects against the progression of AGE-induced endothelial cell dysfunction, may constitute a promising intervention agent against diabetic vascular complications. 3. Chebulic acid significantly reduced the tert-butyl hydroperoxide (t-BHP)-induced cell cytotoxicity, intracellular reactive oxygen species level, and the ratio of GSSH, oxidized form of glutathione (GSH) to the over total GSH (GSH + GSSG) (4.42%) as compared to that with t-BHP alone (8.33%).
BCN3516	Rosamultic acid
1. Rosamultic acid is a class of triterpenes with α-glucosidase inhibitory activity.
BCN3698	Isoderrone
1. Isoderrone is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 22.7 ± 1.7 uM, suggests that it may be a new drug for treatment of type 2 diabetes. 2. Isoderrone shows inhibitory effects on α-glucosidase in vitro.

Alpha-glucosidase inhibitors Bioactivity Products