Products with Anti-migration bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2966 | Tomatine |
| Tomatine is a natural glycoalkaloid with anti-inflammatory, fungicidal, antimicrobial, and insecticidal properties. alpha-Tomatine activates phosphotyrosine kinase and monomeric G-protein signaling pathways leading to Ca(2+) elevation and ROS burst in F. oxysporum cells. | |
| BCN3154 | 6-Hydroxysugiol |
| 1. 6-Hydroxysugiol inhibits proliferation and migration of HepG2 cells and exhibits potent anti-angiogenic activity. | |
| BCN3513 | RA-V |
| 1. RA-V is an potential anti-angiogenic agent, exhibits anti-angiogenic activities in HUVEC and HMEC-1 cell lines with changes in function of these endothelial cells. 2. RA-V has anti-cancer activity, is a potential anti-metastatic agent in breast cancer, and likely acts via PI3K/AKT and NF-κB signaling pathways in both ER-positive and ER-negative breast cancer cells. | |
| BCN3689 | Lusianthridin |
| 1. Lusianthridin shows appreciable cytotoxicity against human lung cancer cell lines. 2. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. | |
| BCN3862 | Escin IA |
| Escin IA is a prodrug and its structure can be converted to desacylescin I by human intestinal bacteria and Lactobacillus brevis., desacylescin I as a biotransformation product shows potentially inhibitory effects on mouse tumor, and a potential candidate for anti tumor agents. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of EMT process by down-regulating LOXL2 expression. | |
